BioCal™ Thermocyclers Calibration Service
BioCal™ Thermocyclers Calibration Service

BioCal™ Thermocyclers Calibration Service is accredited by SAC-SINGLAS

Biofrontier Technology provides on-site calibration for all major brands of thermocyclers. Calibration is performed using a proprietary Mobile Temperature Acquisition System (MTAS).

MTAS is a highly sophisticated temperature measurement system consisting of specially designed hardware that has 16 temperature probes to perform accurate and dynamic multi-channel temperature measurements. Its unique features and capabilities support temperature validation and certification of all kinds and brands of thermal-cycling equipment used for the PCR amplification process.

View our Schedule of Accreditation (CMC Schedule) here.

BioCal™ Thermocyclers Calibration Service helps you to understand the temperature performance of your thermocyclers in terms of:

Deviation ~ difference between set temperature and average block temperature

Uniformity ~ well-to-well difference in temperature

Ramping Rate ~ speed of heating and cooling

Overshoots ~ overheating towards a static temperature plateau

Undershoots ~ overcooling towards a static temperature plateau

By capturing and analysing the temperature performance of your thermocyclers, you will be in control to:

  • Troubleshoot malfunctioning thermocyclers
  • Synchronise protocols between different thermocyclers
  • Determine dynamic boundaries of the assay and  if the thermocycler is within these boundaries
  • Periodically check if the thermocycler still performs as required to be able to generate a reliable result
  • Validate to meet guidelines

BioCal™ on-site calibration service guarantees you with:

  • Highest accuracy in temperature mapping for your thermocyclers
  • Detailed reports with calibration standards & environmental traceability
  • Setup for lowest possible measurement uncertainties
  • Participation in interlaboratory proficiency testing
  • Full service transparency through frequent external audits
  • Trained technicians for optimum support & prompt service

Functional Checks & Cleaning

  • Thorough cleaning of reaction blocks, trays and heat cover
  • Removal of debris from sample wells to optimize heat transfer from block to tubes
  • Confirm thermocycler’s control functions are operative

SAC-SINGLAS Accredited Calibration

  • Thermal measurement range from 30°C to 95°C
  • Temperature accuracy check with readout resolution of 0.001°C
  • Temperature uniformity check via simultaneous measurements of up-to 16 sample wells across the reaction block
  • Reports calibration results for Temperature Deviation, Uniformity, Ramping Rates, Overshoots & Undershoots

BioCal™ Quality Assurance Commitments

  • Back all measurement results with a reliable record of time-temperature data
  • Frequent validation of our sensors to ensure a high level of measurement confidence
  • Attestation of service competency via Proficiency Testing Programs



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