Next Advance Bullet Blender Homogenizer
Next Advance Bullet Blender Homogenizer


The BULLET BLENDER® enables you to homogenize, disrupt, or lyse up to 24 tissue or cell culture samples at a time. Load the samples into standard polypropylene tubes, then place them in the Bullet Blender. The “bullets” in the instrument vigorously strike all of the tubes and homogenize your sample in minutes.


The Bullet Blender is ideal for extraction of proteins, nucleic acids, viruses, small molecules, viable bacteria and more. Samples, along with buffer and beads, are vigorously agitated in individual sample tubes. By tuning the speed and selecting the appropriate material and size of the beads, many types of single cells and organelles can be isolated. Other special applications include lipid extraction from algae for biofuels, liposome preparation for drug delivery and stem cell extraction from adipose.


Discover more products to suit your laboratory needs from Next Advance Product Guide here.




Capacity: Process up to 24 samples in 1.5 or 2.0 mL tubes, up to 12 samples in 5 mL tubes, or up to 8 samples in 50 mL tubes.
Tubes: Uses commonly available tubes.
Environment: Operational in constant 4°C to 50°C. Use in refrigerator/cold room or an incubator.
Cooling: Available to keep samples near 4°C.
Speed Control: Adjustable to handle gentle vortexing to homogenization of bones.
Size: Footprints as small as 9in. (22 cm) wide by 10 in. (25 cm) deep.
Warranty: 2 Years (extended warranties available)


Popular Bullet Blender Models
Models Features Tube Size Sample
Bullet Blender BLUE BBX24B (samples 0-300 µL) 24 sample homogenizer with Air Cooling™ Snap-cap microcentrifuge tubes Up to twenty four 0.01 g to 0.3 g samples
Bullet Blender STORM Pro BT24M (samples 0-300 µL) More powerful homogenizer for tougher samples, with Air Cooling™ Screw-cap & snap-cap microcentrifuge tubes Up to twenty four 0.01 g to 0.3 g samples
Bullet Blender GOLD BB24-AU (samples 0-300 µL) Most powerful homogenization for smaller samples with 4°C cooling and additional noise insulation Screw-cap & snap-cap microcentrifuge tubes Up to twenty four 0.01 g to 0.3 g samples
Bullet Blender STORM 5 BBY5M (samples over 300 µL) For medium size samples 5 mL screw-cap tubes Up to twelve 0.10 g to 1.0 g samples
Bullet Blender 50 GOLD BB50-AU(samples over 300 µL) For larger samples with 4°C cooling and additional noise insulation 50 mL tubes Up to eight 0.10 g to 3.0 g samples


Gold models of the Bullet Blender homogenizers contain a 4°C Cooling™ system. Fill the side compartment with dry ice. When the instrument is running, cold air will blow past the sample tubes. Air circulation will adjust according to homogenization conditions, maintaining the samples near 4°C. If dry ice is not used, ambient temperature air blows past the sample tubes. This Air Cooling™ reduces the heating of the samples.

Blue and Storm model Bullet Blender homogenizers are equipped with Air Cooling™, which draws air into the Bullet Blender, keeping your samples near ambient temperature. This feature is particularly effective if your samples are sensitive to heat and you are using your Bullet Blender in a refrigerator or a cold room. The Air Cooling™ is also useful for preventing the inside of your Bullet Blender unit from heating up if you are running several consecutive homogenization cycles. Air Cooling™ is an option on the microtube models and standard on the 5 mL and the 50 mL tube models.

Consistent and High Yield Results

The BULLET BLENDER homogenizer prepares up to 24 samples in just minutes. All of the samples are automatically homogenized in the same manner, with high yields, so there is very little variation from sample to sample.

 No Cross-Contamination or Sample Loss

There are no probes or blades to cause cross contamination or sample loss, which also means there are no parts to clean between runs. The sample tubes are kept closed and self-contained during homogenization.

Samples Stay COOL

No cool down required. The BULLET BLENDER homogenizers use very little power due to the unique, patented design. There is very little heating of the samples because the sample tubes vibrate vigorously in air, keeping them cool, rather than being subjected to frictional heating as the tubes rub against the walls of a holder. Also, because the motor does not need to agitate any heavy platforms or plates, it is small and will last for many years.

So Easy To Use

Simply place your sample, beads and buffer in standard tubes, and load the tubes into the BULLET BLENDER homogenizer. Tune the extent of disruption by adjusting the run time and speed. Afterwards, place the sample tubes in a centrifuge to separate the lysate. No special holders are needed. There are no clamp plates nor locking rings to fiddle with.

Risk Free Purchase

BULLET BLENDER homogenizers come with a 30 day money back guarantee and a 2 year warranty. The simple, reliable design enables the BULLET BLENDER to sell for one half the price of other agitation based instruments, yet provides an easier, quicker, cooler technique.


All BBX and BBY models are 9 in. (23 cm) wide by 11 in. (28 cm) deep by 8.5 in. (21.5 cm) high

The BB50-DX model is 15 in. (38 cm) wide by 14 in. (35 cm) deep by 15 in. (38 cm) high
The BB24-AU and BB50-AU models are 18 in. (46 cm) wide by 14 in. (35 cm) deep by 15 in (38 cm) high


8.5 to 33 lbs (4 to 15 kg), depending upon model

Run Times:

UP to 5 minutes (15 minutes for the 50-DX and 50-AU). The Bullet Blender will automatically stop after the selected time is up

Power Requirements:

BBX24 and BBX24B models: 24 VDC, 0.75 Amp
BT24M model: 24 VDC, 2.5 Amp
BB24-AU and BB50-DX: 100-240 V, 2.5-4.5 A
Plug configurations for international wall outlets available

Operating Temperature:

4 – 40°C
Relative Humidity:

5 – 90% non-condensing

CE certification

CE certified instruments with upgraded configuration available

The Stomper – Crush tough material in seconds, with no cross-contamination


The Stomper is used to pre-crush hard samples like soybeans, shells, corns prior to dry-grinding in the Bullet Blender. Comes with a sample pack of autoclavable protective shields and with a 1.5mL RINO tube or 5mL tube mortar and pestle set. Mortar and pestle sets are interchangeable and can be ordered separately.

Step 1:    Place your sample in the tube.

Step 2:    Stomp it.

Step 3:    Add grinding beads and homogenize in the Bullet Blender. Your sample will be a fine powder in as little as 5 minutes.






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